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Adenosine A1AR Affinity-Based Probe (AfBP) (AC139)
Cat.#: ASSD-139
Specifications
| Description | Adenosine A1AR Affinity-Based Probe (AfBP) incubate with live cells or membrane fractions can selectively label the desired receptor in the presence of other proteins. AfBP acts as a partial agonist which is highly specific to the A1AR and binds covalently. Apparent pKi values at A1AR are 7.8 and 9.5 (following a 4h preincubation), where a Ki shift indicates a covalent mode of action. |
| Size | 50 μg |
| Applications | For use in confocal microscopy, SDS-PAGE and chemical proteomics profiling applications. |
| Chemical Name | 4-((3-((6-Amino-4-(benzo[d][1,3]dioxol-5-yl)-3,5-dicyanopyridin-2-yl)thio)propyl)(prop-2-yn-1-yl)carbamoyl)benzenesulfonyl fluoride |
| Molecule Weight | 577.6 |
| Molecular formula | C27H20FN5O5S2 |
| PubChem identifier | 167312224 |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
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All of our products
are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.