Cat.#: BBM-C-122
| Source | Brain |
| Disease | Normal |
| Species | Human |
| Cell Type | Endothelial |
| Description | Human Brain Microvascular Endothelial Cells (HBMECs), derived from the human brain, are a specific type of brain endothelial cells that play a crucial role in forming the blood-brain barrier (BBB). They prevent the entry of soluble and cellular substances from the blood into the brain and protect it against toxins and immune cells. These brain microvascular endothelial cells have the ability to display cell adhesion molecules on their surface, which control the migration of leukocytes into the brain. Nevertheless, when there are host-pathogen interactions outside the cells, it can activate calcium signaling within the endothelial cells, leading to the penetration of pathogens through the BBB. Human Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from normal human brain cortical tissue. Each vial contains at least 5×10^5 cells per ml and is delivered frozen. |
| Applications | Human brain microvascular endothelial cells can be used to study the molecular and cellular properties of the blood-brain barrier, or in vitro can be used as the model of the blood-brain barrier (BBB) to study neurological diseases. |
| Quality Control | Human Brain Microvascular Endothelial Cells test negative for bacteria, yeast, fungi, and mycoplasma. |
| Shipping and Storage | Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage. Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended. |
| Cat.# | Name | Description | Price |
|---|---|---|---|
| BBM-C-132 | Porcine Brain Microvascular Endothelial Cells |
Porcine Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from healthy porcine brain tissue. Porcine Brain Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with a gelatin-based solution for 0.5 hours and incubated in Ace Therapeutics’s Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
|
inquiry |
| BBM-C-144 | Rat Astrocytes |
Rat Astrocytes (RA) from Ace Therapeutics are isolated from postnatal day 2 rat brains and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
|
inquiry |
| BBM-C-150 | Rabbit Astrocytes |
Rabbit Astrocytes from Ace Therapeutics are isolated from rabbit brains and are cryopreserved at passage one. Rabbit Astrocytes are characterized by immunofluorescence with antibody specific to GFAP. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
|
inquiry |
| BBM-C-147 | Rat Astrocytes-midbrain |
Rat astrocytes-midbrain (RA-mb) from Ace Therapeutics are isolated from CD® IGS rat midbrain and are cryopreserved at P0. RA-mb are characterized by immunofluorescence with antibodies specific to GFAP. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
|
inquiry |
| BBM-C-127 | C57BL/6 Mouse Brain Microvascular Endothelial Cells |
C57BL/6 mouse brain endothelial cells (MBREC) from Ace Therapeutics are isolated from the brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
| BBM-C-126 | C57BL/6 Mouse Embryonic Brain Endothelial Cells |
C57BL/6 Mouse Embryonic Brain Endothelial Cells from Ace Therapeutics are isolated from brain tissue of pathogen-free laboratory mice at embryonic day 14.5-19. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
| BBM-C-137 | Rabbit Cerebrovascular Pericytes Cells |
Rabbit Cerebrovascular Pericytes from Ace Therapeutics are isolated from the brain tissue of a pathogen-free New Zealand White Rabbit. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
| BBM-C-133 | Canine Brain Microvascular Endothelial Cells |
Canine Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from the brain of a pathogen-free laboratory beagle dog. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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inquiry |
| BBM-C-148 | Rat Astrocytes-adult |
Rat Astrocytes-adult (RA-a) from Ace Therapeutics are isolated from adult CD® IGS rat brains and are cryopreserved after purification. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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inquiry |
| BBM-C-146 | Sprague-Dawly (SD) Rat Astrocytes |
Characterization: 1. Cell Activity;
– Recovery Viability ≥ 80%.
2. Cell Purity;
– GFAP-positive cells ≥ 70%.
– β-tubulin III- or doublecortin- (Dcx-) positive cells ≤ 10%.
– GalC-positive cells ≤ 10%.
|
inquiry |
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.