Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                TASP0233278 is a potent and orally active V1B receptor antagonist with antidepressant and anxiolytic activities in rodents.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C30H31ClFN3O7S
                             
                                                                        
                                                                        
                                                                Molecular Weight
                                                                632.1004
                             
                                                                        
                                                                Elemental Analysis
                                                                C, 57.01; H, 4.94; Cl, 5.61; F, 3.01; N, 6.65; O, 17.72; S, 5.07
                             
                                                                        
                                                                Synonym
                                                                TASP0233278; TASP 0233278; TASP-0233278;
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                (2S,4R)-1-((R)-5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxoindolin-3-yl)-4-fluoro-N,N-dimethylpyrrolidine-2-carboxamide
                             
                                                                        
                                                                InChi Key
                                                                DKGOINZYRASALR-WEWKHQNJSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C30H31ClFN3O7S/c1-33(2)28(36)24-15-19(32)17-34(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)35(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24H,15,17H2,1-5H3/t19-,24+,30+/m1/s1
                             
                                                                        
                                                                SMILES Code
                                                                O=C(N1S(=O)(C2=CC=C(OC)C=C2OC)=O)[C@](N3C[C@H](F)C[C@H]3C(N(C)C)=O)(C4=CC=CC=C4OC)C5=C1C=CC(Cl)=C5
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                To be determined
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                To be determined
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001