Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                Product Name
                                                                URB597 (KDS-4103)
                             
                                                                                                                    
                                                                Size
                                                                10.0mg; 25.0mg; 50.0mg
                             
                                                                        
                                                                        
                                                                        
                                                                Description
                                                                URB597, also known as KDS-4103, is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).  FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. In pre-clinical laboratory tests researchers found URB597 increased the production of endocannabinoids resulting in measurable antidepressant and analgesic effects.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C20H22N2O3
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 70.99; H, 6.55; N, 8.28; O, 14.18
                             
                                                                        
                                                                Synonym
                                                                URB597, URB-597, URB 597, KDS-4103, KDS4103, KDS 4103
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
                             
                                                                        
                                                                InChi Key
                                                                ROFVXGGUISEHAM-UHFFFAOYSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
                             
                                                                        
                                                                SMILES Code
                                                                O=C(OC1=CC=CC(C2=CC=CC(C(N)=O)=C2)=C1)NC3CCCCC3
                             
                                                                        
                                                                Appearance
                                                                White to off-white solid powder
                             
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO, not in water
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001