Related Diseases
                                                                Schizophrenia
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                ABT-288 is a  histamine receptor 3 (H3) antagonist potentially for the treatment of Alzhermer's disease.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C23H24N4O
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 74.17; H, 6.49; N, 15.04; O, 4.30
                             
                                                                        
                                                                Synonym
                                                                ABT-288; ABT288; ABT 288
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                2-[4-[4-[(3aR,6aR)-5-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[3,2-c]pyrrol-1-yl]phenyl]phenyl]pyridazin-3-one
                             
                                                                        
                                                                InChi Key
                                                                GNIRITULTPTAQW-KNQAVFIVSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C23H24N4O/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27/h2-11,13,19,22H,12,14-16H2,1H3/t19-,22+/m1/s1
                             
                                                                        
                                                                SMILES Code
                                                                O=C1C=CC=NN1C2=CC=C(C3=CC=C(N4CC[C@]5([H])CN(C)C[C@@]54[H])C=C3)C=C2
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001