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AZD8926

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Specification

Cat. No.

SMD1415

Related Diseases

Schizophrenia

Product Name

AZD8926

Size

Customizable

Price

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Description

AZD8926 is a potent and selective GSK3β inhibitor (glycogen synthase kinase-3β). AZD8926 has potential for treating several CNS disorders, such as Alzheimer’s disease (AD), schizophrenia, and chronic as well as acute neurodegenerative diseases.

CAS Number

933785-68-3 (free base)

Chemical Formula

C25H27F4N7O2

Exact Mass

533.2162

Molecular Weight

533.5316

Elemental Analysis

C, 56.28; H, 5.10; F, 14.24; N, 18.38; O, 6.00

Synonym

AZD8926; AZD-8926; AZD 8926.

IUPAC/Chemical Name

(4-((5-fluoro-4-(1-(tetrahydro-2H-pyran-4-yl)-2-(trifluoromethyl)-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone

InChi Key

JKLMQKZMMRJQCK-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H27F4N7O2/c1-34-8-10-35(11-9-34)22(37)16-2-4-17(5-3-16)32-24-31-14-19(26)21(33-24)20-15-30-23(25(27,28)29)36(20)18-6-12-38-13-7-18/h2-5,14-15,18H,6-13H2,1H3,(H,31,32,33)

SMILES Code

O=C(C1=CC=C(NC2=NC=C(F)C(C3=CN=C(C(F)(F)F)N3C4CCOCC4)=N2)C=C1)N5CCN(C)CC5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.