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Bifeprunox Mesylate

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Specification

Cat. No.

SMD1440

Related Diseases

Schizophrenia

Product Name

Bifeprunox Mesylate

Size

5.0mg; 10.0mg; 25.0mg

Price

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Availability

2 Weeks

Description

Bifeprunox, also known as DU-127090, is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox influences nicotine-seeking behaviour in response to drug-associated stimuli in rats. Bifeprunox suppresses in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation.

CAS Number

350992-13-1 (mesylate)

Chemical Formula

C25H27N3O5S

Molecular Weight

481.567

Elemental Analysis

C, 62.35; H, 5.65; N, 8.73; O, 16.61; S, 6.66

Synonym

Bifeprunox; Bifeprunox Mesylate; DU-127090; DU 127090; DU127090.

IUPAC/Chemical Name

7-(4-(Biphenyl-3-ylmethyl)piperazin-1-yl)benzoxazol-2(3H)-one methanesulfonate

InChi Key

ONWKHSGOYGLGPO-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H23N3O2.CH4O3S/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19;1-5(2,3)4/h1-11,16H,12-15,17H2,(H,25,28);1H3,(H,2,3,4)

SMILES Code

O=C1OC2=C(N3CCN(CC4=CC(C5=CC=CC=C5)=CC=C4)CC3)C=CC=C2N1.CS(=O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.