Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                Product Name
                                                                Brofaromine Hydrochloride
                             
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                Brofaromine Hydrochloride is a reversible inhibitor of monoamine oxidase A and acts on epinephrine , norepinephrine, serotonin, and dopamine. The compound was primarily researched in the treatment of depression and anxiety. Brofaromine also acts as a serotonin reuptake inhibitor, and its dual pharmacologic effects offered promise in the treatment of a wide spectrum of depressed patients while producing less severe anticholinergic side effects in comparison with older standard drugs like the tricyclic antidepressants. Unlike standard MAOIs, possible side effects do not include cardiovascular complications (hypertension) with encephalopathy, liver toxicity or hyperthermia.
                             
                                                                        
                                                                CAS Number
                                                                63638-90-4 (HCl)
                             
                                                                        
                                                                Chemical Formula
                                                                C14H17BrClNO2
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 48.51; H, 4.94; Br, 23.05; Cl, 10.23; N, 4.04; O, 9.23
                             
                                                                        
                                                                Synonym
                                                                Brofaromine Hydrochloride; Brofaromine HCl; CGP-11305A; CGP-11305A.
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine hydrochloride
                             
                                                                        
                                                                InChi Key
                                                                PUYKEOGYPYITCW-UHFFFAOYSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C14H16BrNO2.ClH/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11;/h6-9,16H,2-5H2,1H3;1H
                             
                                                                        
                                                                SMILES Code
                                                                c12c(c(cc(c2)OC)Br)oc(c1)C1CCNCC1.Cl
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO, not in water
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001