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CGP 55845

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Specification

Cat. No.

SMD1446

Related Diseases

Schizophrenia

Product Name

CGP 55845

Size

Customizable

Price

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Description

CGP 55845 is a potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively).

CAS Number

150175-54-5 (free base)

Chemical Formula

C18H22Cl2NO3P

Exact Mass

401.0714

Molecular Weight

402.25

Elemental Analysis

C, 53.75; H, 5.51; Cl, 17.63; N, 3.48; O, 11.93; P, 7.70

Synonym

CGP 55845; CGP-55845; CGP55845

IUPAC/Chemical Name

Phosphinic acid, ((2S)-3-(((1S)-1-(3,4-dichlorophenyl)ethyl)amino)-2- hydroxypropyl)(phenylmethyl)-

InChi Key

ZODSPDOOCZZEIM-BBRMVZONSA-N

InChi Code

InChI=1S/C18H22Cl2NO3P/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14/h2-9,13,16,21-22H,10-12H2,1H3,(H,23,24)/t13-,16-/m0/s1

SMILES Code

O=P(CC1=CC=CC=C1)(C[C@@H](O)CN[C@H](C2=CC=C(Cl)C(Cl)=C2)C)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.