Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                Product Name
                                                                Clomipramine HCl
                             
                                                                                                                    
                                                                        
                                                                        
                                                                        
                                                                Description
                                                                Clomipramine HCl inhibitor of mAChRs, 5-HT2/3/6/7 receptors, α1/2-adrenergic receptors, SERT, NET, and hERG K and L-type Ca channels used to treat depression, anxiety, narcolepClomipramine HCl sy, and obessive-compulisve disorder. It also acts as a FIASMA, decreases thermal and mechanical pain, and may prolong the cardiac QT interval.
                             
                                                                        
                                                                CAS Number
                                                                17321-77-6 (HCl)
                             
                                                                        
                                                                Chemical Formula
                                                                C19H24Cl2N2
                             
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 64.96; H, 6.89; Cl, 20.18; N, 7.97
                             
                                                                        
                                                                Synonym
                                                                Anafranil; Clomicalm; G-34586; G34586; G 34586; Hydiphen
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
                             
                                                                        
                                                                InChi Key
                                                                WIMWMKZEIBHDTH-UHFFFAOYSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
                             
                                                                        
                                                                SMILES Code
                                                                CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.[H]Cl
                             
                                                                        
                                                                Appearance
                                                                White to off-white crystalline powder.
                             
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001