Related Diseases
                                                                Schizophrenia
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist. It provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C26H24ClFN4O
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 67.45; H, 5.23; Cl, 7.66; F, 4.10; N, 12.10; O, 3.46
                             
                                                                        
                                                                Synonym
                                                                CP-465022; CP 465022; CP465022; UNII-4582JTR93Y.
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                4(3H)-Quinazolinone, 3-(2-chlorophenyl)-2-(2-(6-((diethylamino)methyl)-2-pyridinyl)ethenyl)-6-fluoro-
                             
                                                                        
                                                                InChi Key
                                                                HYHNPUGUPISSQO-FYWRMAATSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C26H24ClFN4O/c1-3-31(4-2)17-20-9-7-8-19(29-20)13-15-25-30-23-14-12-18(28)16-21(23)26(33)32(25)24-11-6-5-10-22(24)27/h5-16H,3-4,17H2,1-2H3/b15-13+
                             
                                                                        
                                                                SMILES Code
                                                                CCN(CC)Cc1cccc(n1)/C=C/c2nc3ccc(cc3c(=O)n2c4ccccc4Cl)F
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO, not in water
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001