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α-Cyperone

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Specification

Cat. No.

SMD1259

Related Diseases

Depression

Product Name

α-Cyperone

Size

10.0mg; 25.0mg; 50.0mg; 100.0mg

Price

Inquiry

Availability

2 Weeks

Description

α-Cyperone is a sesquiterpenoid that has been found in C. rotundus rhizomes and has diverse biological activities. It inhibits LPS-induced nuclear translocation of the NF-κB subunit p65, as well as LPS-induced production of prostaglandin E2 (PGE2) and IL-6, in RAW 264.7 cells. α-Cyperone (15 and 30 µM) reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in SH-SY5Y cells. It reduces the production of the hepatitis B surface antigen (HBsAG) in infected HepG2 2.2.15 cells (IC50 = 274.7 µM).

CAS Number

473-08-5

Chemical Formula

C15H22O

Exact Mass

218.1671

Molecular Weight

218.34

Elemental Analysis

C, 82.52; H, 10.16; O, 7.33

Synonym

α-Cyperone; α Cyperone; (+)-α-Cyperone; (+)-α Cyperone; (+) α-Cyperone; (+) α Cyperone;

IUPAC/Chemical Name

(4aS,7R)-1,4a-dimethyl-7-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one

InChi Key

KUFXJZXMWHNCEH-DOMZBBRYSA-N

InChi Code

InChI=1S/C15H22O/c1-10(2)12-5-7-15(4)8-6-14(16)11(3)13(15)9-12/h12H,1,5-9H2,2-4H3/t12-,15+/m1/s1

SMILES Code

C[C@]12C(C[C@H](C(C)=C)CC1)=C(C)C(CC2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.