Related Diseases
                                                                Schizophrenia
                             
                                                                                                                    
                                                                Product Name
                                                                Desmethyl cariprazine
                             
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                Desmethyl Cariprazine Hydrochloride is a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C20H30Cl2N4O
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 58.11; H, 7.32; Cl, 17.15; N, 13.55; O, 3.87
                             
                                                                        
                                                                Synonym
                                                                Desmethyl cariprazine; Dcar; UNII-286RCD7025;
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                Urea, N-(trans-4-(2-(4-(2,3-dichlorophenyl)-1-piperazinyl)ethyl)cyclohexyl)-N'-methyl-
                             
                                                                        
                                                                InChi Key
                                                                WMQLLTKSISGWHQ-WKILWMFISA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C20H30Cl2N4O/c1-23-20(27)24-16-7-5-15(6-8-16)9-10-25-11-13-26(14-12-25)18-4-2-3-17(21)19(18)22/h2-4,15-16H,5-14H2,1H3,(H2,23,24,27)/t15-,16-
                             
                                                                        
                                                                SMILES Code
                                                                O=C(NC)N[C@H]1CC[C@H](CCN2CCN(C3=CC=CC(Cl)=C3Cl)CC2)CC1
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >3 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.03.00