Related Diseases
                                                                Insomnia
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                Difemetorex (INN; sold as Cleofil), also known as diphemethoxidine, is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C23H30N2O3
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 72.22; H, 7.91; N, 7.32; O, 12.55
                             
                                                                        
                                                                Synonym
                                                                Difemetorex; BRN 1651678; JB 8035; Diphemetoxidine; Difemetorexum; BA 18189;
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                3-(3,4-dimethylpiperazin-1-yl)propyl 2-hydroxy-2,2-diphenylacetate
                             
                                                                        
                                                                InChi Key
                                                                IVGNNRSXOKVDQE-UHFFFAOYSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C23H30N2O3/c1-19-18-25(16-15-24(19)2)14-9-17-28-22(26)23(27,20-10-5-3-6-11-20)21-12-7-4-8-13-21/h3-8,10-13,19,27H,9,14-18H2,1-2H3
                             
                                                                        
                                                                SMILES Code
                                                                OC(C1=CC=CC=C1)(C2=CC=CC=C2)C(OCCCN3CC(C)N(C)CC3)=O
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001