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Encenicline HCl salt

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Specification

Cat. No.

SMD1490

Related Diseases

Schizophrenia

Product Name

Encenicline HCl salt

Size

5.0mg; 10.0mg; 25.0mg; 50.0mg

Price

Inquiry

Availability

2 Weeks

Description

Encenicline, also known as EVP-6124 and MT-4666, is a novel α7 nicotinic acetylcholine receptor agonist that enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens. EVP-6124 improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.

CAS Number

550999-74-1 (HCl)

Chemical Formula

C16H18Cl2N2OS

Exact Mass

356.0517

Molecular Weight

357.3

Elemental Analysis

C, 53.79; H, 5.08; Cl, 19.84; N, 7.84; O, 4.48; S, 8.97

Synonym

EVP-6124; EVP 6124; EVP6124; MT-4666; MT4666; MT 4666; Encenicline HCl.

IUPAC/Chemical Name

(R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride.

InChi Key

OIJYTJGIDVTCFF-ZOWNYOTGSA-N

InChi Code

InChI=1S/C16H17ClN2OS.ClH/c17-12-3-1-2-11-8-14(21-15(11)12)16(20)18-13-9-19-6-4-10(13)5-7-19;/h1-3,8,10,13H,4-7,9H2,(H,18,20);1H/t13-;/m0./s1

SMILES Code

O=C(C1=CC2=CC=CC(Cl)=C2S1)N[C@H]3CN4CCC3CC4.[H]Cl

Appearance

white to off-white solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.