Related Diseases
                                                                Insomnia
                             
                                                                        
                                                                Related Diseases
                                                                Bipolar Disorder
                             
                                                                        
                                                                                                                    
                                                                Product Name
                                                                Lurasidone HCl
                             
                                                                                                                    
                                                                Size
                                                                1.0g; 2.0g; 5.0g; 10.0g; 20.0g; 50.0g; Click to view more sizes and prices
                             
                                                                        
                                                                        
                                                                        
                                                                Description
                                                                Lurasidone HCl, also known as SM-13496, is an atypical antipsychotic drug. In the USA since 2013, it is also approved for the treatment of depressive episodes associated with bipolar I disorder as well as bipolar II disorder in adults when used alone or in combination with lithium, valproate, or lamotrigine.  Lurasidone may be useful for treating the cognitive and memory deficits seen in schizophrenia.  Lurasidone has activity at several serotonin receptors that are involved in learning and memory.
                             
                                                                        
                                                                CAS Number
                                                                367514-88-3 (HCl)
                             
                                                                        
                                                                Chemical Formula
                                                                C28H37ClN4O2S
                             
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 63.56; H, 7.05; Cl, 6.70; N, 10.59; O, 6.05; S, 6.06
                             
                                                                        
                                                                Synonym
                                                                SM-13496; SM 13496; SM13496; Lurasidone HCl. trade name Latuda.
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                (3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
                             
                                                                        
                                                                InChi Key
                                                                NEKCRUIRPWNMLK-SCIYSFAVSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/m0./s1
                             
                                                                        
                                                                SMILES Code
                                                                O=C1N(C[C@H]2[C@H](CN3CCN(C4=NSC5=C4C=CC=C5)CC3)CCCC2)C([C@]6([H])[C@@](C7)([H])CC[C@@]7([H])[C@]16[H])=O.[H]Cl
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO, not in water
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001