Products

Inquiry

First Name *

Last Name *

Business Email *

Phone

Company/Institution

Job Title

Services or Products of Interest *

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Org-34517

Inquiry

Specification

Cat. No.

SMD1072

Related Diseases

Depression

Product Name

Org-34517

Size

Customizable

Price

Inquiry

Description

Org-34517 is a glucocorticoid receptor (GR) antagonist potentially for the treatment of depression

CAS Number

189035-07-2

Chemical Formula

C28H30O4

Exact Mass

430.2144

Molecular Weight

430.54

Elemental Analysis

C, 78.11; H, 7.02; O, 14.86

Synonym

Org-34517; SCH-900636; Org34517; SCH900636; Org 34517; SCH 900636

IUPAC/Chemical Name

(8S,11R,13S,14S,17S)-11-(benzo[d][1,3]dioxol-5-yl)-17-hydroxy-13-methyl-17-(prop-1-yn-1-yl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

InChi Key

DFELGYQKEOCHOA-BZAFBGKRSA-N

InChi Code

InChI=1S/C28H30O4/c1-3-11-28(30)12-10-23-21-7-4-17-13-19(29)6-8-20(17)26(21)22(15-27(23,28)2)18-5-9-24-25(14-18)32-16-31-24/h5,9,13-14,21-23,30H,4,6-8,10,12,15-16H2,1-2H3/t21-,22+,23-,27-,28-/m0/s1

SMILES Code

O=C1CCC2=C3[C@@H](C4=CC=C(OCO5)C5=C4)C[C@]6(C)[C@@](C#CC)(O)CC[C@@]6([H])[C@]3([H])CCC2=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.