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Pirlindole-d4 HCl

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Specification

Cat. No.

SMD1103

Related Diseases

Depression

Product Name

Pirlindole-d4 HCl

Size

1.0mg

Price

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Availability

2 Weeks

Description

Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 µM independent of MAO-A activity.

CAS Number

1801617-88-8

Chemical Formula

C15H15D4ClN2

Exact Mass

266.1488

Molecular Weight

266.8054

Elemental Analysis

C, 67.53; H, 8.69; Cl, 13.29; N, 10.50

Synonym

Pirlindole-d4 HCl; Pirlindole d4 HCl;

IUPAC/Chemical Name

8-methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole-1,1,2,2-d4 hydrochloride

InChi Key

LIFOOCLGAAEVIF-UVSTZUAESA-N

InChi Code

InChI=1S/C15H18N2.ClH/c1-10-5-6-14-12(9-10)11-3-2-4-13-15(11)17(14)8-7-16-13;/h5-6,9,13,16H,2-4,7-8H2,1H3;1H/i7D2,8D2;

SMILES Code

CC1=CC=C2N3C([2H])(C([2H])(NC4CCCC(C2=C1)=C34)[2H])[2H].Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.