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Pirlindole free base

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Specification

Cat. No.

SMD1122

Related Diseases

Depression

Product Name

Pirlindole free base

Size

10.0mg; 25.0mg; 50.0mg

Price

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Availability

2 Weeks

Description

Pirlindole is a reversible inhibitor of monoamine oxidase A (RIMA) which was developed and is used in Russia as an antidepressant. It is structurally and pharmacologically related to metralindole. Pirlindole is approved in some European and non-European countries for the treatment of depression. Pirlindole has an absolute bioavailability of between 20 and 30% due to an extensive first-pass effect. Orally, the Tmax varies between 2.5 and 6 h in the rat and 0.8 and 2 h in the dog.

CAS Number

60762-57-4 (free base)

Chemical Formula

C15H18N2

Exact Mass

226.147

Molecular Weight

226.323

Elemental Analysis

C, 79.61; H, 8.02; N, 12.38

Synonym

Pirlindole. Lifril, Pyrazidol,

IUPAC/Chemical Name

2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole

InChi Key

IWVRVEIKCBFZNF-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H18N2/c1-10-5-6-14-12(9-10)11-3-2-4-13-15(11)17(14)8-7-16-13/h5-6,9,13,16H,2-4,7-8H2,1H3

SMILES Code

CC1=CC2=C(C=C1)N3C4=C2CCCC4NCC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.