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Posovolone

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Specification

Cat. No.

SMD1091

Related Diseases

Depression

Product Name

Posovolone

Size

25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

Inquiry

Availability

2 Weeks

Description

Posovolone, also known as Co 134444, is a GABAA receptor positive allosteric modulator. It is also an antidepressant. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects.

CAS Number

256955-84-7 (free base)

Chemical Formula

C26H40N2O3

Exact Mass

428.3039

Molecular Weight

428.617

Elemental Analysis

C, 72.86; H, 9.41; N, 6.54; O, 11.20

Synonym

Posovolone; CO-134444; CO-134444; CO134444;

IUPAC/Chemical Name

1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3-(methoxymethyl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-(1H-imidazol-1-yl)ethan-1-one

InChi Key

BRVGKZNQWCQKTC-MVCIVNJCSA-N

InChi Code

InChI=1S/C26H40N2O3/c1-24-10-11-26(30,16-31-3)14-18(24)4-5-19-20-6-7-22(25(20,2)9-8-21(19)24)23(29)15-28-13-12-27-17-28/h12-13,17-22,30H,4-11,14-16H2,1-3H3/t18-,19-,20-,21-,22+,24-,25-,26+/m0/s1

SMILES Code

C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(CN5C=CN=C5)=O)([H])C[C@](COC)(O)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.