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                                                                Depression
                             
                                                                                                                    
                                                                Product Name
                                                                Ro 25-6981 free base
                             
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                Ro 25-6981 is a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit.
                             
                                                                        
                                                                CAS Number
                                                                169274-78-6 (free base)
                             
                                                                        
                                                                Chemical Formula
                                                                C22H29NO2
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 77.84; H, 8.61; N, 4.13; O, 9.43
                             
                                                                        
                                                                Synonym
                                                                Ro 25-6981; Ro25-6981; Ro-25-6981; Ro-256981; Ro 256981; Ro256981;  Ro 25-6981 free base
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl)phenol
                             
                                                                        
                                                                InChi Key
                                                                WVZSEUPGUDIELE-HTAPYJJXSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C22H29NO2/c1-17(22(25)20-7-9-21(24)10-8-20)16-23-13-11-19(12-14-23)15-18-5-3-2-4-6-18/h2-10,17,19,22,24-25H,11-16H2,1H3/t17-,22+/m0/s1
                             
                                                                        
                                                                SMILES Code
                                                                O[C@@H](C1=CC=C(O)C=C1)[C@@H](C)CN2CCC(CC3=CC=CC=C3)CC2
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO, not in water
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001