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SB 221284

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Specification

Cat. No.

SMD1157

Related Diseases

Depression

Product Name

SB 221284

Size

Customizable

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Description

SB 221284 is potent, selective 5-HT2C/2B receptor antagonist. SB 221284 are pKi values are 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors respectively.

CAS Number

196965-14-7

Chemical Formula

C16H14F3N3OS

Exact Mass

353.081

Molecular Weight

353.36

Elemental Analysis

C, 54.38; H, 3.99; F, 16.13; N, 11.89; O, 4.53; S, 9.07

Synonym

SB 221284; SB221284; SB-221284.

IUPAC/Chemical Name

5-methylsulfanyl-N-pyridin-3-yl-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide

InChi Key

OQZOXHCRSXYSPM-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H14F3N3OS/c1-24-14-7-10-4-6-22(13(10)8-12(14)16(17,18)19)15(23)21-11-3-2-5-20-9-11/h2-3,5,7-9H,4,6H2,1H3,(H,21,23)

SMILES Code

O=C(N1CCC2=C1C=C(C(F)(F)F)C(SC)=C2)NC3=CC=CN=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.