Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                Description
                                                                SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist which is being investigated for its antidepressant effects. Relative to the selective serotonin reuptake inhibitors (SSRIs), SB-649,915 has a faster onset of action and may also have greater clinical efficacy.
                             
                                                                        
                                                                        
                                                                Chemical Formula
                                                                C26H29N3O3
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 72.37; H, 6.77; N, 9.74; O, 11.12
                             
                                                                        
                                                                Synonym
                                                                SB 649915; SB-649915; SB649915.
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
                             
                                                                        
                                                                InChi Key
                                                                PJSUYRBCBFPCQW-UHFFFAOYSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C26H29N3O3/c1-18-5-7-21-22(27-18)3-2-4-24(21)31-14-13-29-11-9-19(10-12-29)15-20-6-8-25-23(16-20)28-26(30)17-32-25/h2-8,16,19H,9-15,17H2,1H3,(H,28,30)
                             
                                                                        
                                                                SMILES Code
                                                                O=C1COC2=CC=C(CC3CCN(CCOC4=C5C=CC(C)=NC5=CC=C4)CC3)C=C2N1
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001