Inquiry

First Name *

Last Name *

Business Email *

Phone

Company/Institution

Job Title

Services or Products of Interest *

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

SB236057

Inquiry

Specification

Cat. No.

SMD1198

Related Diseases

Depression

Product Name

SB236057

Size

Customizable

Price

Inquiry

Description

SB236057 is a potent and selective inverse agonist for the serotonin receptor 5-HT, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in serotonin levels in the brain, and was originally researched as a potential antidepressant. SB-236,057 also acts as a potent teratogen, producing severe musculoskeletal birth defects when rodents were exposed to it during pregnancy.

CAS Number

180083-49-2

Chemical Formula

C33H34N4O3

Exact Mass

534.2631

Molecular Weight

534.66

Elemental Analysis

C, 74.13; H, 6.41; N, 10.48; O, 8.98

Synonym

SB236057 ; SB-236057; SB 236057.

IUPAC/Chemical Name

(1'-ethyl-6,7-dihydro-2H,5H-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)(2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-yl)methanone

InChi Key

WXAKEEQOWUHGCI-UHFFFAOYSA-N

InChi Code

InChI=1S/C33H34N4O3/c1-4-36-15-12-33(13-16-36)20-39-30-18-25-11-14-37(29(25)19-28(30)33)32(38)24-7-5-23(6-8-24)27-10-9-26(17-21(27)2)31-35-34-22(3)40-31/h5-10,17-19H,4,11-16,20H2,1-3H3

SMILES Code

O=C(N1CCC2=C1C=C3C(OCC34CCN(CC)CC4)=C2)C5=CC=C(C6=CC=C(C7=NN=C(C)O7)C=C6C)C=C5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.