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SRA880 free base

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Specification

Cat. No.

SMD1174

Related Diseases

Depression

Product Name

SRA880 free base

Size

Customizable

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Description

SRA880 is a non-peptide somatostatin sst(1) receptor antagonist. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine D4 receptors. SRA880 positively modulates release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.

CAS Number

187218-90-2 (free base)

Chemical Formula

C26H32N4O4

Exact Mass

464.2424

Molecular Weight

464.57

Elemental Analysis

C, 67.22; H, 6.94; N, 12.06; O, 13.78

Synonym

SRA880; SRA 880; SRA-880; NVP-SRA880; NVP SRA880; NVPSRA880.

IUPAC/Chemical Name

[(3R,4aR,10aR)-6-methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-3-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone

InChi Key

INULNSAIIZKOQE-YOSAUDMPSA-N

InChi Code

InChI=1S/C26H32N4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33/h3-9,19-20,24H,10-17H2,1-2H3/t19-,20-,24-/m1/s1

SMILES Code

O=C([C@H]1CN(C)[C@]2([H])CC3=CC=CC(OC)=C3C[C@@]2([H])C1)N4CCN(C5=CC=C([N+]([O-])=O)C=C5)CC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.