Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                                                                    
                                                                        
                                                                        
                                                                        
                                                                Description
                                                                Traxoprodil, also known as CP-101606 and CP 98113, is a NR2B N-Methyl-D-Aspartate (NMDA) antagonist potentially for the treatment of major depressive. Traxoprodil potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Traxoprodil decreases pentylenetetrazol-induced seizures.
                             
                                                                        
                                                                CAS Number
                                                                134234-12-1 (free base)
                             
                                                                        
                                                                Chemical Formula
                                                                C20H25NO3
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 73.37; H, 7.70; N, 4.28; O, 14.66
                             
                                                                        
                                                                Synonym
                                                                Traxoprodil; CP-101606; CP101606; CP 101606; CP 98113.
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol
                             
                                                                        
                                                                InChi Key
                                                                QEMSVZNTSXPFJA-HNAYVOBHSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1
                             
                                                                        
                                                                SMILES Code
                                                                O[C@@H](C1=CC=C(O)C=C1)[C@H](C)N2CCC(C3=CC=CC=C3)(O)CC2
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001