Related Diseases
                                                                Depression
                             
                                                                                                                    
                                                                Product Name
                                                                WAY-100135 hydrochloride
                             
                                                                                                                    
                                                                        
                                                                        
                                                                        
                                                                Description
                                                                WAY-100135 hydrochloride is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1A. It is selective for 5-HT1A over 5-HT1B, 5-HT1C, and 5-HT2 receptors, as well as dopamine D1 and D2, and α1-, α2-, and β-adrenergic receptors. WAY-100135 hydrochloride increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.
                             
                                                                        
                                                                CAS Number
                                                                149007-54-5 (hydrochloride)
                             
                                                                        
                                                                Chemical Formula
                                                                C24H35Cl2N3O2
                             
                                                                        
                                                                        
                                                                        
                                                                Elemental Analysis
                                                                C, 61.53; H, 7.53; Cl, 15.13; N, 8.97; O, 6.83
                             
                                                                        
                                                                Synonym
                                                                WAY-100135 hydrochloride; WAY 100135 hydrochloride; WAY100135 hydrochloride; (S)-WAY-100135 hydrochloride; (S)-WAY100135 hydrochloride; (S)-WAY 100135 hydrochloride;
                             
                                                                        
                                                                IUPAC/Chemical Name
                                                                (S)-N-(tert-butyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)-2-phenylpropanamide dihydrochloride
                             
                                                                        
                                                                InChi Key
                                                                VJGZNBYDSDEOED-FAVHNTAZSA-N
                             
                                                                        
                                                                InChi Code
                                                                InChI=1S/C24H33N3O2.2ClH/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4;;/h5-13,20H,14-18H2,1-4H3,(H,25,28);2*1H/t20-;;/m1../s1
                             
                                                                        
                                                                SMILES Code
                                                                COC1=C(C=CC=C1)N2CCN(C[C@@H](C(NC(C)(C)C)=O)C3=CC=CC=C3)CC2.Cl.Cl
                             
                                                                        
                                                                        
                                                                Purity
                                                                >98% (or refer to the Certificate of Analysis)
                             
                                                                        
                                                                Shipping Condition
                                                                Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                             
                                                                        
                                                                Storage Condition
                                                                Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                             
                                                                        
                                                                Solubility
                                                                Soluble in DMSO
                             
                                                                        
                                                                Shelf Life
                                                                >2 years if stored properly
                             
                                                                        
                                                                Drug Formulation
                                                                This drug may be formulated in DMSO
                             
                                                                        
                                                                Stock Solution Storage
                                                                0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
                             
                                                                        
                                                                HS Tariff Code
                                                                2934.99.9001