In the pathological mechanism of stroke, damage caused by excitotoxicity, oxidative stress, and mitochondrial dysfunction may induce multiple cell signaling cascades, causing nerve cells to undergo programmed or unprogrammed death. Cell death and apoptosis antibodies are widely used as a research tool to explore the regulation of these cell signaling pathways. By intervening in these pathways, it can help protect nerve cells from further damage caused by stroke and promote the recovery and regeneration of neurological function.