Glial Cell Marker Antibodies

Ace Therapeutics is committed to providing a comprehensive catalog of high-quality glial marker antibodies for stroke research at cost-effective prices. Our comprehensive product catalog includes GFAP antibodies, CD11b antibodies, Iba1 antibodies, and corresponding ELISA kits. These antibodies and kits all are rigorously validated, high quality, and cost-effective, making them ideal for stroke research.

Glial cells are the major non-neuronal cell types of the central nervous system, including astrocytes, oligodendrocytes, and microglia. Glial cell markers are specific proteins or molecules that are important tools in the stroke field to identify and study different glial cell populations. A typical example is that in the early stage after stroke, astrocytes are activated and release a variety of cytokines, participating in the inflammatory response and neural repair process. In addition, astrocytes also facilitate signaling between neurons and provide nutrients and support that neurons require.

• GFAP, the full name is glial fibrillary acidic protein, is a protein found in astrocytes. GFAP is involved in maintaining the structure and function of astrocytes and plays a role in regulating the blood-brain barrier, providing support to neurons, and responding to injury and damage to the central nervous system. Increased GFAP expression is often associated with astrocyte activation in response to various brain injuries. Therefore, it is used as a marker to study astrocyte reactivity and assess its relationship to stroke.
• Iba1, the full name is Ionized calcium-binding adapter molecule 1, is a calcium ion binding adapter molecule. Iba1 is commonly used to label microglia which are the main immune cells of the brain, working with neurons and other glial cells to support and maintain normal function of the nervous system. Through immunohistochemical staining or fluorescent labeling of Iba1, the presence, and viability of microglia can be detected and localized in tissue sections or cell cultures to study the inflammatory and immune responses associated with stroke.
• S100B is a protein produced primarily in the central nervous system, primarily in astrocytes. Elevated levels of S100B in the blood are associated with brain injuries, such as traumatic brain injury, stroke, and neurodegenerative diseases. Additionally, S100B has been explored as a potential biomarker for predicting brain injury severity and assessing prognosis.

Please access the following our all-series glial cell marker antibodies or contact our scientist for personalized assistance.