Synaptic Marker Antibodies

Ace Therapeutics is committed to supplying high-quality synaptic marker antibodies for stroke research to our clients at cost-effective prices. Our antibodies are specifically designed to target and detect key synaptic markers relevant to stroke research such as synaptophysin, PSD95, and neuroligin. Researchers can visualize and quantify changes in synaptic density, integrity, and function after a stroke, thus understanding the mechanisms underlying stroke-induced synaptic dysfunction and identifying potential therapeutic targets.

Synapse refers to the connection point between a neuron and other cells (usually another neuron) and is a key structure in the nervous system for transmitting information. They allow communication and transfer of information between neurons and between neurons and other cells. Normal synaptic function is critical for normal brain function and cognitive processes. Synapses are divided into two types: chemical synapses and electrical synapses. Chemical synapses transmit signals through a chemical called a neurotransmitter, while electrical synapses transmit signals through an electric current.

• Postsynaptic density protein 95 (PSD-95) is a scaffolding protein that plays a crucial role in synapse development and function. Antibodies against PSD-95 are often used to label and quantify synaptic density alterations.
• Synaptophysin is a synaptic vesicle protein that is involved in neurotransmitter release. Antibodies against synaptophysin can help assess synaptic integrity and plasticity in stroke-affected brain regions.
• The GluR1 subunit of the AMPA receptor is crucial for excitatory synaptic transmission. Antibodies targeting GluR1 can reveal changes in glutamate receptor composition and distribution after stroke.
• Gephyrin is a protein involved in anchoring inhibitory neurotransmitter receptors at synapses. Antibodies against gephyrin can assess alterations in inhibitory synaptic transmission following stroke.

Please access the following our all-series synaptic markers antibodies or contact our scientist for personalized assistance.