Neuronal Damage and Repair

Stroke-related neuronal damage, known as excitotoxicity, is a process in which glutamate receptors, especially N-methyl-D-aspartate (NMDA) receptors, are overactivated. This results in an influx of calcium ions into neurons, triggering multiple downstream signaling cascades, including the mitogen-activated protein kinase (MAPK) pathway, the phospholipase A2 (PLA2) pathway, and the apoptotic pathway. Neuronal damage and repair-related antibodies help to study related molecules and signaling pathways in the process of neuronal repair and regeneration, understand the mechanism of neuronal damage, providing clues for the development of new methods to treat stroke.

Neuronal Damage and Repair

Please access our full range of neuronal damage and repair-related antibodies for stroke research or contact our scientist for personalized assistance.

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Antibodies for Stroke Research

  1. Qin C, Yang S, Chu YH, et al. Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions. Signal Transduct Target Ther. 2022, 7(1):215.
  2. Shen Z, Xiang M, Chen C, et al. Glutamate excitotoxicity: Potential therapeutic target for ischemic stroke. Biomed Pharmacother. 2022, 151:113125.
  3. Guan R, Zou W, Dai X, et al. Mitophagy, a potential therapeutic target for stroke. J Biomed Sci. 2018, 25(1):87.
All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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